Dr. Rajalakshmi P
Additional Professor, Department of Pathology, SCTIMST, Trivandrum, Kerala
MCQ
1. What is the pathology?
A. Lhermitte Duclos disease
B. Ganglioglioma
C. Medulloblastoma
D. Friedreich's ataxia
2. Name the syndrome associated with this disease.
A. Tuberous sclerosis
B. Carney complex
C. Von Hippel-Lindau syndrome
D. Cowden syndrome
3. Typical MRI appearance of cerebellum in this condition
A. Tiger stripe or striated pattern
B. Grape-like or nodular pattern
C. Hot cross bun sign
D. Dural tail Sign
4. What is the other name of this condition? ......................................
Published on 12 Oct 2026.
Answer key
1. A
2. D
3. A
4. Dysplastic cerebellar gangliocytoma
Key diagnostic feature - Dysplastic cerebellar gangliocytoma
1. Grossly thickened cerebellar folia, but without loss of folial appearance.
2. Altered microscopic architecture with loss of internal granule neurons and Purkinje cells.
3. Replacement by ganglion cells which are positive for neuronal markers: NeuN, MAP2, neurofilament.
4. Presence of abnormal myelinated axons in outer molecular layer.
1.Image is of Lhermitte-Dulcis disease
2. Associated with Cowden syndrome
3. MRI shows tiger striped pattern
4. Also called as Dysplastic cerebellar gangliocytoma
Lhermitte Duclos disease
Cowden syndrome
Tiger stripe or striated pattern
1. Lhermitte duclos disease
2.Cowden syndrome
3.Tiger stripe or striated pattern
4.Dysplastic gangliocytoma of cerebellum
1. A. Lhermitte Duclos disease
2. D. Cowden syndrome
3. A. Tiger stripe or striated pattern
4. Dysplastic cerebellar gangliocytoma
1. Ganglioglioma
2. Cowden Syndrome
3. Tiger stripe or striated pattern
4. Glioneuronal tumor
Lhermitte Duclos disease, Cowden syndrome, Tiger stripe or striated pattern
1. B
2. A
3. C
Lhermitte Duclos disease
Cowden syndrome
Tiger stripe or striated appearance
Dysplastic cerebellar neurocytoma
1.Lhermitte Duclos disease
2.Cowden syndrome
3.Tiger stripe or striated pattern
1A; 2D; CA; 4. Dysplastic Cerebellar Gangliocytoma
Answers to MCQs..
1. Lhermitte Duclos Disease
2. Cowden syndrome
3. Tiger strip or striated pattern
4. Dysplastic cerebellar gangliocytoma
1. A
2. D
3. A
4. Dysplastic cerebellar gangliocytoma
1. A. Lhermitte-Duclos disease
2. D. Cowden syndrome
3. A. Tiger-stripe or striated pattern
4. Synonymous with Dysplastic cerebellar gangliocytoma
I.A – Lhermite duclos disease
2.D- cowden syndrome
3.A – Tiger stripe or striated pattern
4.Dysplastic cerebellar gangliocytoma